Increasing Physical Activity for Adults With Multiple Sclerosis (MS)

Increasing Physical Activity Via Provider Prescription and Engagement: Efficacy of ExerciseRx for Adults With Multiple Sclerosis (MS)

Status unknownNot a drug-phase studyMS (type not specified)NCT06270641

What it found

Paper found, not read

A paper reports the results; we have not read it yet. See Papers below.

What was tested

Treatment tested

  • ExerciseRx intervention

What it measured

Main measures

  • Physical activity: daily average step count

    Baseline and week 13

    Physical function

Other measures (10)

  • Activity volume

    Baseline, weeks 13 and 26

    Physical function

  • Minutes/week of moderate intensity aerobic activity

    Baseline, weeks 13 and 26

    Physical functionSafety

  • Fatigue - PROMIS Fatigue-MS Short Form 8a

    Baseline, weeks 13 and 26

    FatiguePhysical function

  • Pain intensity - PROMIS Pain Intensity Short Form 3a

    Baseline, weeks 13 and 26

    Physical functionPain

  • Depressive symptom severity - PROMIS Depression Short Form 8a

    Baseline, weeks 13 and 26

    Physical functionMood and sleep

  • Sleep disturbance - PROMIS Sleep Disturbance Short Form 6a

    Baseline, weeks 13 and 26

    Physical functionMood and sleep

  • Physical functioning - PROMIS Physical Function 10a

    Baseline, weeks 13 and 26

    Physical function

  • Pain interference - PROMIS Pain Interference Scale Short Form 6a

    Baseline, weeks 13 and 26

    Physical functionPain

  • Social participation - PROMIS Satisfaction with Social Roles and Activities Short Form 8a

    Baseline, weeks 13 and 26

    Physical functionQuality of life (reported by participants)

  • Social participation - PROMIS Ability to Participate in Social Roles and Activities Short Form 8a

    Baseline, weeks 13 and 26

    Physical function

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* Provider-confirmed diagnosis of MS using revised 2017 McDonald criteria * > 18+ years of age * Patient determined disease steps (PDDS) score \< 3, indicating the potential for some gait disability although typically ambulates without an assistive device * Insufficiently active, defined as \< 150 minutes of physical activity per week, assessed using the PAVS in the EHR in clinics as part of the routine patient intake process * Use of an iPhone with software version iOS13+ or an Android phone 4.1+ * Agree to install and use the ExerciseRx app for the entire study period and keep their phone on them during the daytime (e.g., pocket, bags, hands)

Exclusion criteria

* Recent (past 4 weeks) or planned surgery during the study period which may impact engaging in step counts * MS relapse within the last 30 days * Plans to travel internationally during the study period, which could interfere with server uploads of mobile phone data * Those at a higher risk of falling or injury from falls or unable to safely exercise due to other medical conditions (e.g. heart conditions, diabetes or conditions made worse by walking or physical activity)

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients with multiple sclerosis (MS).

Papers

Loading reviews and guidelines…

History

    1. Started

      Feb 2024

    2. Main results due

      Apr 2025

    3. Finished

      Sept 2026

    Assembled by software from public sources.