Investigation of the Effectiveness of Craniosacral Therapy in Patients

Investigation of the Effectiveness of Craniosacral Therapy in Patients With Multiple Sclerosis: A Randomized Controlled, Single-Blind Study

Status unknownNot a drug-phase studyMS (type not specified)NCT06292312

We could not find results for this trial

What it found

No results found

We found no results in the registry or in papers.

What was tested

Treatment tested

  • Craniosacral therapy

Given to everyone in the trial

  • Conventional physiotherapy

What it measured

Main measures

  • Dynamic posturography

    Change from baseline at 8 weeks treatment program and two months after.

    Walking and mobility

  • Heart rate variability

    Change from baseline at 8 weeks treatment program and two months after.

  • Number of participants

    Change from baseline at 8 weeks treatment program and two months after.

Other measures (5)

  • Pain level

    Change from baseline at 8 weeks treatment program and two months after.

    Pain

  • Central sensitization

    Change from baseline at 8 weeks treatment program and two months after.

    Bladder, bowel and sexual function

  • Fatigue

    Change from baseline at 8 weeks treatment program and two months after.

    Fatigue

  • Sleep quality

    Change from baseline at 8 weeks treatment program and two months after.

    Myelin repairMood and sleep

  • Life quality

    Change from baseline at 8 weeks treatment program and two months after.

    FatiguePainQuality of life (reported by participants)

Who could take part

MS (type not specified) · 18 to 65 · EDSS 1 to 5.5

Show the full criteria

Inclusion criteria

* 18 to 65 years old * Definitive diagnosis of MS by a neurologist * EDSS score between 1-5.5 * Not receiving active physical therapy services * Volunteering.

Exclusion criteria

* Having a neurological disease other than MS * Attacks in the last three months * Corticosteraoid use * History of surgery on the spine * Central and peripheral nervous system disease * Pregnancy * Oncological diseases * Severe comorbid somatic and psychiatric disorders * Receiving invasive/manipulative treatment.

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Although the cause of Multiple Sclerosis (MS), one of the common demyelinating diseases of the central nervous system, has not yet been fully elucidated, autonomic nervous system dysfunction has been suggested in its etiology. Symptoms such as fatigue, problems with bladder, bowel, cardiovascular, sleep, sexual and sweating functions, abnormal sympathetic skin response or decreased heart rate variation support this hypothesis. In the treatment of many neurological diseases such as Multiple Sclerosis, complementary medicine practices and non-traditional therapies have recently been shown to be effective in addition to conventional practices. One of these practices, craniosacral therapy (CST), uses manual palpation and manipulation of the craniosacral system to influence sensory, motor, cognitive and emotional processes in the nervous system. In addition, it is thought that applying external force to certain bone elements can have a positive effect on various symptoms in patients with MS, based on the knowledge that it can be transmitted within the system.

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History

    1. Started

      Feb 2024

    2. Main results due

      Apr 2025

    3. Finished

      May 2025

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