Motor-cognitive Performance in People With Multiple Sclerosis
Motor-cognitive Performance in People With Multiple Sclerosis - Brain Activity and Effects of Balance Exercise
What it found
No result yet.
What was tested
Treatment tested
- HiBalance-MS
What it measured
Main measures
Mini Balance Evaluation Systems test.
Pre intervention baseline and post intervention at 10 weeks.
Walking and mobility
Other measures (29)
10-Meter Walk Test, maximum speed.
Pre intervention baseline and post intervention at 10 weeks.
Walking and mobility10-Meter Walk Test, self-selected speed.
Pre intervention baseline and post intervention at 10 weeks.
Walking and mobility2-Minute Walk Test, self-selected speed.
Pre intervention baseline and post intervention at 10 weeks.
Walking and mobilityGait speed during simultaneous dual task performance.
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memoryWalking and mobilityStride length during dual task gait performance.
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memoryWalking and mobilityStep time during dual task gait performance.
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memoryWalking and mobilityResponse errors in dual task cognitive performance
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memoryWalking and mobilityReaction time in dual task cognitive performance
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memoryWalking and mobilitySix-Spot Step Test.
Pre intervention baseline and post intervention at 10 weeks.
Walking and mobilityCompletion time in the Trail Making Test.
Pre intervention baseline and post intervention at 10 weeks.
Thinking and memory
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* an MS diagnosis according to McDonald criteria; * an overall MS-disability score from 2.0 to 5.5 according to the Expanded Disability Status Scale; * ability to walk 100 m without aid; * a maximum score of 24 in the Mini-BESTest (i.e., \< 25 points) * 18 to 65 years of age
Exclusion criteria
* cognitive impairment as indicated by a score \<21 in the Montreal Cognitive Assessment; * presence of other conditions that would substantially influence balance; * an MS relapse or change of disease-modifying treatment within the past 8 weeks
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
Having a neurological disease such as multiple sclerosis (MS) leads to difficulties in balance and gait with or without concurrent performance of cognitive tasks, hindering activity performance and influencing the possibilities for an independent lifestyle. The investigators have adapted a previously developed balance training program to a highly challenging program specifically directed to MS (HiBalance-MS). This program was recently tested and found feasible in a pilot study. The investigators will now perform a randomized controlled trial in people with MS, in order to determine the effects of the program. The hypothesis is that progressively challenging balance exercise programs that are specific to the balance control domains affected by MS will be effective to improve balance control, walking, motor-cognitive performance, activity performance and health related quality of life.
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History
Started
Feb 2024
Main results due
Dec 2025
Finished
Aug 2027