Implementation of Online Mindfulness-Based Stress Reduction Tailored f

Implementation of Online Mindfulness-Based Stress Reduction Tailored for People with Multiple Sclerosis

Not yet recruitingNot a drug-phase studyEarly (CIS/RIS)NCT06415552

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Mindfulness-Based Stress Reduction

What it measured

Main measures

  • Recruitment

    24 months

  • Retention

    24 months

    Feasibility

  • Adherence

    24 months

    Quality of life (reported by participants)

  • Follow-up rates

    24 months

Other measures (14)

  • Quality of Life using the Multiple Sclerosis Impact Scale (MSIS-29)

    Measured at baseline, 8-week follow-up, and 3-month follow-up

    Quality of life (reported by participants)

  • Quality of Life using the EuroQol (EQ-5D-5L)

    Measured at baseline, 8-week follow-up, and 3-month follow-up

    Quality of life (reported by participants)

  • Anxiety

    Measured at baseline, 8-week follow-up, and 3-month follow-up

    Mood and sleep

  • Depression

    Measured at baseline, 8-week follow-up, and 3-month follow-up

    Mood and sleep

  • Health services use

    Measured at baseline, 8-week follow-up, and 3-month follow-up

  • Emotion regulation

    Measured at baseline, 8-week follow-up, and 3-month follow-up

  • Self-compassion

    Measured at baseline, 8-week follow-up, and 3-month follow-up

  • Mindfulness

    Measured at baseline, 8-week follow-up, and 3-month follow-up

  • Climate

    Measured at baseline, 8-week follow-up, and 3-month follow-up

  • Therapeutic alliance

    Measured at baseline, 8-week follow-up, and 3-month follow-up

Who could take part

Early (CIS/RIS) · 18 to 60

Show the full criteria

Inclusion criteria

1. Age >18 years \</= 60 years 2. Diagnosis of MS or related condition (Clinically Isolated Syndrome, Neuromyelitis Optica Spectrum Disorder, Chronic Inflammatory Demyelinating Neuropathy) 3. Able to understand spoken and written English 4. Willing to take part in an MBSR course

Exclusion criteria

1. Cognitive impairment (\<26 on the Montreal Cognitive Assessment) 2. Severe active mental health impairment (psychosis, suicidality) 3. Medical instability (terminal/life threatening inter-current illness)

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

This project aims to implement and investigate a mindfulness-based stress reduction (MBSR) in people with multiple sclerosis (PwMS). The main objective is to implement MBSR intervention for PwMS in a major tertiary care clinic for PwMS. We will iteratively refine the intervention as required based on stakeholder feedback and any other emergent contextual findings. Participants will be asked to take part in an 8-week MBSR course and report changes in anxiety, depression, quality of life, emotional regulation, self-compassion, mindfulness, and health services use.

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History

    1. Started

      Jan 2025

    2. Main results due

      Dec 2026

    3. Finished

      May 2027

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