Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulat
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS - a Pilot Study
What it found
No result yet.
What was tested
Treatment tested
- Transcutaneous Electrical Nerve Stimulation
- Movement
What it measured
Main measures
BOLD activation due to TENS
1 hour fMRI scan
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* age: 18-65 years * EDSS score \< 7
Exclusion criteria
* metal or electrical implants * BMI > 40 * claustrophobia * being pregnant * having a psychiatric disorder * having cognitive or communication problems which reduces the capacity to understand instructions * having a neurological disorder other than MS * having cardiac arrhythmia
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis. However, extensive use of TENS in a clinical setting is hindered by a lack of neurophysiological understanding of the effects of TENS. The primary objective of this pilot study is therefore to investigate the effects of TENS on brain activity in pwMS measured with fMRI.
Papers
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History
Started
Oct 2025
Main results due
Dec 2025
Finished
Dec 2025