Task Specific Training for Advanced Multiple Sclerosis
The Effect of Task Specific Physical Therapy for Persons With Advanced Multiple Sclerosis
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Task specific physical therapy
What it measured
Main measures
Multiple Sclerosis Physical Frailty Functional Assessment (MSPFFA)
Will be administered twice, once at pre-intervention and once at post-intervention. The length of the intervention is 6 weeks.
Walking and mobility
Other measures (1)
Multiple Sclerosis Impact Scale-29 (MSIS29)
Will be administered twice, once at pre-intervention and once at post-intervention. The length of the intervention is 6 weeks.
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 75 · EDSS 7.0 to 8.0
Show the full criteria
Inclusion criteria
1. definitive diagnosis of Multiple Sclerosis 2. Expanded Disability Status Scale (EDSS) of 7.0-8.0 3. Ability to read, understand , and sign an informed consent -
Exclusion criteria
1. evidence of MS exacerbation in the 4 weeks prior to starting the study 2. any orthopedic, cardiopulmonary, or non-MS neurologic symptoms that will interfere with their ability to participate in the study
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The purpose of this study is to find effective physical therapy treatments for individuals who have severe multiple sclerosis. Physical therapy treatments for mild-to-moderate multiple sclerosis exists, however, very limited research has been done for physical therapy for severe multiple sclerosis (MS). In this study 10 participants diagnosed with severe MS will engage in 1-hour physical therapy sessions twice a week for 6 weeks to address limitations in standing, balancing, and bed mobility.
Papers
Background
Kalb R, Brown TR, Coote S, Costello K, Dalgas U, Garmon E, Giesser B, Halper J, Karpatkin H, Keller J, Ng AV, Pilutti LA, Rohrig A, Van Asch P, Zackowski K, Motl RW. Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course. Mult Scler. 2020 Oct;26(12):1459-1469. doi: 10.1177/1352458520915629. Epub 2020 Apr 23.Background
Arya KN, Verma R, Garg RK, Sharma VP, Agarwal M, Aggarwal GG. Meaningful task-specific training (MTST) for stroke rehabilitation: a randomized controlled trial. Top Stroke Rehabil. 2012 May-Jun;19(3):193-211. doi: 10.1310/tsr1903-193.
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History
Started
Jul 2024
Main results due
Dec 2025
Finished
Jan 2026