Investigating Visuo-spatial Abilities and Psychological Effects in Wes
Investigating Visuo-spatial Abilities and Psychological Effects in West Nile and Multiple Sclerosis Patients with a Focus on a Possible Rehabilitation Protocol
We could not find results for this trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Mindlenses Professional
Compared with
- Conventional rehabilitation
What it measured
Main measures
Measure of changes in cognitive performance after the treatment
At baseline and after 2 weeks (post-intervention)
Thinking and memory
Other measures (1)
Measure of changes in psychological aspects after the treatment
At baseline and after 2 weeks (post-intervention)
Mood and sleep
Who could take part
MS (type not specified) · 20 to 85
Show the full criteria
Inclusion criteria
* Diagnosis of: Multiple Scleroris OR vWN infection ascertained by laboratory analysis and received no later than twelve months prior to the date of hospitalization * preserved use of at least one hand * normal or corrected to normal vision
Exclusion criteria
* history of psychiatric and/or concurrent neurological diseases * inability to provide informed consent, * impaired comprehension of oral instructions,
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The study aims to investigate visuospatial abilities and psychological outcomes in patients with multiple scleroris (MS) and patients with West Nile virus infection (vWN). Patients will undergo a specific neuropsychological and psychological evaluation. Afterwards, patients will receive 10 sessions of cognitive training integrating digital exercises and prismatic lenses. At the end of the treatment, patients will be re-evaluated to explore for potential changes in the cognitive and psychological profile.
Papers
Background
Bracco M, Mangano GR, Turriziani P, Smirni D, Oliveri M. Combining tDCS with prismatic adaptation for non-invasive neuromodulation of the motor cortex. Neuropsychologia. 2017 Jul 1;101:30-38. doi: 10.1016/j.neuropsychologia.2017.05.006. Epub 2017 May 6.Background
Carson PJ, Konewko P, Wold KS, Mariani P, Goli S, Bergloff P, Crosby RD. Long-term clinical and neuropsychological outcomes of West Nile virus infection. Clin Infect Dis. 2006 Sep 15;43(6):723-30. doi: 10.1086/506939. Epub 2006 Aug 10.Background
Chiaravalloti ND, DeLuca J, Moore NB, Ricker JH. Treating learning impairments improves memory performance in multiple sclerosis: a randomized clinical trial. Mult Scler. 2005 Feb;11(1):58-68. doi: 10.1191/1352458505ms1118oa.Background
Chiaravalloti ND, DeLuca J. Cognitive impairment in multiple sclerosis. Lancet Neurol. 2008 Dec;7(12):1139-51. doi: 10.1016/S1474-4422(08)70259-X.Background
Hayes EB, Sejvar JJ, Zaki SR, Lanciotti RS, Bode AV, Campbell GL. Virology, pathology, and clinical manifestations of West Nile virus disease. Emerg Infect Dis. 2005 Aug;11(8):1174-9. doi: 10.3201/eid1108.050289b.Background
Magnani B, Caltagirone C, Oliveri M. Prismatic adaptation as a novel tool to directionally modulate motor cortex excitability: evidence from paired-pulse TMS. Brain Stimul. 2014 Jul-Aug;7(4):573-9. doi: 10.1016/j.brs.2014.03.005. Epub 2014 Apr 13.Background
Pisella L, Rode G, Farne A, Tilikete C, Rossetti Y. Prism adaptation in the rehabilitation of patients with visuo-spatial cognitive disorders. Curr Opin Neurol. 2006 Dec;19(6):534-42. doi: 10.1097/WCO.0b013e328010924b.Background
Rao SM, Leo GJ, Bernardin L, Unverzagt F. Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction. Neurology. 1991 May;41(5):685-91. doi: 10.1212/wnl.41.5.685.
Loading reviews and guidelines…
History
- Status changed from Recruiting to Status unknown
- Result signal changed from Ongoing to Status unknown
Started
Sept 2022
Main results due
Dec 2024
Finished
Dec 2024