Virtual Memory Attention and Problem Solving Skills for Persons With MS (MAPSS-MS) Pilot

Not yet recruitingNot a drug-phase studyMS (type not specified)NCT06709768

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Virtual Memory, Attention, and Problem Solving Skills for Persons with MS (MAPSS-MS)

What it measured

Main measures

  • Neurocognitive Function -Objective

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Thinking and memorySafety
  • Perceived Cognitive Function PROMIS v2.0 - Cognitive Function-Abilities Short Form 8a

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Thinking and memory

Other measures (7)

  • Self-Efficacy for Cognitive Tasks

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Thinking and memory
  • Depressive Symptoms - CES-D 10

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Mood and sleep
  • Compensatory Strategies

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Thinking and memory
  • Perceived Stress

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

  • Pain Symptoms

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Pain
  • Fatigue

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Fatigue
  • Sleep

    This measure will be completed at baseline, following the 8 week intervention and 6 weeks after the intervention is complete.

    Mood and sleep

Who could take part

MS (type not specified) · 21 to 85

Show the full criteria

Inclusion criteria

Inclusion Criteria: Age 21 -85 years old, reside in the United States, MS diagnosis for at least 1 years, access and ability to use phone, computer and Internet, Score of ≥10 on the Perceived Deficits Questionnaire (PDQ), adequate vision and motor skills to use the computer for testing and to participate in the intervention. Exclusion Criteria:A diagnosis of dementia/head injury, inability to speak English, severe functional limitation that makes use of computer for intervention and testing impossible; prior participation in a cognitive rehab intervention during the last year; currently using Brain HQ at home. -

Exclusion criteria

Not separately supplied in the registry.

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

The goal of this pilot clinical trial is to study is to test the feasibility and effects of a virtual (remote) version of a cognitive rehabilitation intervention - Memory, Attention, and Problem Solving Skills for Persons with MS (MAPSS-MS). We have already tested this intervention "in person" and found it to be effective at helping persons with MS improve their cognitive function learn. We are now testing the MAPSS-MS intervention using a virtual or remote format. The main questions this pilot study aims to answer are: 1. What is the feasibility of the Virtual MAPSS-MS intervention 2. Compared with persons in the wait list control group, will persons receiving the Virtual MAPSS-MS intervention have better overall neurocognitive function and 3. ) Compared with persons in the wait list control group, will persons receiving the Virtual MAPSS-MS intervention have improved stress, self-efficacy for cognitive everyday tasks, use of compensatory strategies and improved depressive symptoms, fatigue, sleep and pain. Participants will be asked to take part in the MAPSS-MS intervention virtually and complete surveys and cognitive tests online at three time points: before the eight-week intervention, immediately after the intervention and six-weeks after the intervention. The virtual MAPSS-MS has two components (a) Group sessions via zoom with an expert leader and (b) a computer assisted brain games (Brain HQ) program. The eight online group sessions (2 hours once per week) will address common cognitive concerns experienced by persons with MS and strategies that may be helpful. Participants will also be provided access to Brain HQ, a computerized training program, and asked to practice these games for 20-30 minutes on 5 or 6 days per week.

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History

    1. Started

      Dec 2024

    2. Main results due

      May 2025

    3. Finished

      Nov 2025

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