Development and Assessment of a Vocational Rehabilitation Intervention for Job Retention in Workers With Multiple Sclerosis (RiaLSM Intervention Project)

RecruitingNot a drug-phase studyMS (type not specified)NCT06805318

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Vocational Rehabilitation intervention for pwMS

What it measured

Main measures

  • Interception

    Up to 6 months

  • Acceptance

    Up to 6 months

  • Adherence

    Up to 6 months

    Quality of life (reported by participants)
  • Lost to Follow-Up

    Up to 6 months

  • Canadian Occupational Performance Measure (COPM)

    Baseline, up to 6 months

    Quality of life (reported by participants)
  • Client Satisfaction Questionnaire (CSQ)

    Up to 6 months

    Quality of life (reported by participants)
  • Global Perceived Effect (GPE) scale

    Up to 6 months

    Quality of life (reported by participants)
  • Barthel Index (BI)

    Baseline, up to 6 months

    Walking and mobilityBladder, bowel and sexual function
  • Hospital Anxiety Depression scale (HADS)

    Baseline, up to 6 months

    Mood and sleep
  • Modified Fatigue (MFIS-21)

    Baseline, up to 6 months

    Thinking and memoryFatigue
  • Multiple Sclerosis Neuropsychological Questionnaire for patient (MSNQ-p)

    Baseline, up to 6 months

    Thinking and memory
  • WHO Disability Assessment Schedule (WHODAS)

    Baseline, up to 6 months

    Thinking and memoryWalking and mobility

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* Confirmed MS diagnosis * Age ≥18 years * Currently employed at the beginning of the study entry * Have worked at least one day in the last 12 months * MSQ-Job >=15 * Written informed consent

Exclusion criteria

* Presence of other pathologies impacting on work productivity

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system with both inflammatory and degenerative characteristics that affects approximately 136,000 people in Italy. The highest incidence of disease onset occurs between the ages of 20 and 40, which corresponds to the most productive period of a person's life. For this reason, one of the main social consequences of MS is the reduction or abandonment of work activity, which often begins in the early stages of the disease. Vocational Rehabilitation (VR) interventions, as reported in the literature, are used to manage and reduce work-related difficulties. The goal of VR is to enable individuals who experience difficulties in performing work activities to access, find, and maintain employment. This approach is characterized by its multi-professional and multidimensional nature, involving different types of interventions carried out by various professionals in diverse settings. The overall aim of the project is to define a Vocational Rehabilitation (VR) protocol to reduce work-related challenges and promote job retention for workers with MS within the Italian healthcare and social context. The intervention will be organised into three different areas: rehabilitation, reasonable accommodation and education. Participants will receive any of the three interventions or a combination of these. The study will involve a multidisciplinary team of doctors (e.g. neurologist, physiatrist), psychologists, occupational therapists, physiotherapists, social workers, and labour law experts who will be involved according to the subject's specific needs.

Papers

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History

    1. Started

      Jan 2025

    2. Main results due

      Oct 2025

    3. Finished

      Oct 2025

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