Effect of Training With Wireless Lightning Reaction Systems on Cogniti
Effects of Agility and Cognitive Training With Reaction System on Cognitive Functions and Walking in Individuals With Multiple Sclerosis
What it found
No result yet.
What was tested
Treatment tested
- Wireless Lighting Reaction System Training(Agility plus Cognitive)
What it measured
Main measures
Cognitive Functions
8th week
Thinking and memory
Other measures (14)
Balance assessment
8th week
Walking and mobilityAnxiety and Depression Status
8th week
Mood and sleepFatigue Assessment
8th week
FatiguePhysical functionMS Quality of Life
8th week
Quality of life (reported by participants)Static Posture Assessment(Static Balance)
8th week
Walking and mobilityStatic Posture Assessment(Visual Dependency)
8th week
VisionWalking and mobilityStatic Posture Assessment(Proprioception Disturbance)
8th week
Static Posture Assessment(Vestibular Dominant)
8th week
Walking and mobilityGait Analysis(Step length)
8th week
Walking and mobilityGait Analysis(Stride length)
8th week
Walking and mobility
Who could take part
MS (type not specified) · 18 to 55
Show the full criteria
Inclusion criteria
* Being between the ages of 18-55 * Having a definite MS diagnosis according to the 2017 McDonald criteria. * EDSS score of 4 or below * Being able to communicate (speaking and understanding Turkish, no speech disorders)
Exclusion criteria
* Regular exercise in the last 6 months * Having an MS attack in the last month * Having an MS attack during the study period * Presence of additional accompanying neurological diseases * Use of dalfampridine * Use of antipsychotic and psychostimulant drugs * Drug and alcohol addiction * Pregnancy, breastfeeding * No chronic systemic disease preventing exercise * Patients who cannot reach the targeted exercise level
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
When the literature is examined, balance disorders, walking disorders and cognitive problems are frequently observed in Multiple Sclerosis(MS) patients. Using technologically supported equipment such as reaction systems, cognitive function measurements have been successfully performed in the elderly, and improvements in reaction times have been detected in athletes when used for training purposes. The primary aim of the study is to provide improvement in agility and cognitive functions in patients using a technology-supported reaction device. In addition, it aims to improve balance function assessed with static posturography and gait parameters assessed with gait analysis by increasing sensory input and shortening reaction time. As a result of the agility and cognitive training performed, we aim to provide improvement in MS-related quality of life and decrease in disability.
Papers
Background
Matsuda PN, Shumway-Cook A, Ciol MA, Bombardier CH, Kartin DA. Understanding falls in multiple sclerosis: association of mobility status, concerns about falling, and accumulated impairments. Phys Ther. 2012 Mar;92(3):407-15. doi: 10.2522/ptj.20100380. Epub 2011 Dec 1.Background
Martin CL, Phillips BA, Kilpatrick TJ, Butzkueven H, Tubridy N, McDonald E, Galea MP. Gait and balance impairment in early multiple sclerosis in the absence of clinical disability. Mult Scler. 2006 Oct;12(5):620-8. doi: 10.1177/1352458506070658.Background
Pollock AS, Durward BR, Rowe PJ, Paul JP. What is balance? Clin Rehabil. 2000 Aug;14(4):402-6. doi: 10.1191/0269215500cr342oa.Background
Prosperini L, Castelli L. Spotlight on postural control in patients with multiple sclerosis. Degener Neurol Neuromuscul Dis. 2018 Apr 3;8:25-34. doi: 10.2147/DNND.S135755. eCollection 2018.Background
Iqbal K. Mechanisms and models of postural stability and control. Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:7837-40. doi: 10.1109/IEMBS.2011.6091931.Background
Creath R, Kiemel T, Horak F, Jeka JJ. The role of vestibular and somatosensory systems in intersegmental control of upright stance. J Vestib Res. 2008;18(1):39-49.Background
Melillo F, Di Sapio A, Martire S, Malentacchi M, Matta M, Bertolotto A. Computerized posturography is more sensitive than clinical Romberg Test in detecting postural control impairment in minimally impaired Multiple Sclerosis patients. Mult Scler Relat Disord. 2017 May;14:51-55. doi: 10.1016/j.msard.2017.03.008. Epub 2017 Mar 23.Background
Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983 Nov;33(11):1444-52. doi: 10.1212/wnl.33.11.1444.Background
Givon U, Zeilig G, Achiron A. Gait analysis in multiple sclerosis: characterization of temporal-spatial parameters using GAITRite functional ambulation system. Gait Posture. 2009 Jan;29(1):138-42. doi: 10.1016/j.gaitpost.2008.07.011. Epub 2008 Oct 31.Background
Thoumie P, Lamotte D, Cantalloube S, Faucher M, Amarenco G. Motor determinants of gait in 100 ambulatory patients with multiple sclerosis. Mult Scler. 2005 Aug;11(4):485-91. doi: 10.1191/1352458505ms1176oa.
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History
Started
Jan 2026
Main results due
May 2026
Finished
Aug 2026