Illuminating New Paths in the Treatment of Multiple Sclerosis Relapses
Illuminating New Paths in the Treatment of Multiple Sclerosis Relapses - Early and Specialized Rehabilitation
What it found
No result yet.
What was tested
Treatment tested
- Intensive rehab
Compared with
- Usual care
What it measured
Main measures
Expanded Disability Status Scale (EDSS)
Change from Baseline to 52 weeks
Disability progressionMS Functional Composite (MSFC) Score
Change from Baseline to 52 weeks
Disability progression
Other measures (13)
MS Functional Composite (MSFC) Score
Changes from Baseline to 2 weeks and 10 weeks
Disability progressionHandgrip strength
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Arm and hand functionPhysical functionSix spot step test (SSST)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Walking and mobilityFive times sit to stand chair rise test (5STS)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Five times sit to stand chair rise test muscle power (5STS_power)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Physical functionPatient determined disease steps (PDDS)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Walking and mobilityQuality of life (reported by participants)MS Walking Scale (MSWS)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Walking and mobilityQuality of life (reported by participants)Falls Efficacy Scale International (short FES-I)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Walking and mobilityQuality of life (reported by participants)Functional Assessment of MS (FAMS)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
Quality of life (reported by participants)Modified Fatigue Impact Scale (MFIS)
Changes from Baseline to 2 weeks, 10 weeks, and 52 weeks
FatigueQuality of life (reported by participants)
Who could take part
MS (type not specified) · 18 and over
Show the full criteria
Inclusion criteria
* admitted to the Danish MS Hospitals for an inpatient rehabilitation stay * confirmed motor relapse (within the past 6 months) by a neurologist, with disability/ functional interference characterized by change in pyramidal, and/or cerebellar functional scores of 2 or higher * completed steroid or other acute relapse treatment, if prescribed * age over 18 years
Exclusion criteria
* more than 6 months since onset of motor relapse * medical conditions or substantial cognitive impairments that hinder participation in the study (e.g. inability to perform or understand the intensive rehabilitation) * pregnancy
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
The overall purpose of this project is to develop and test an infrastructure that can ensure early and specialized rehabilitation for individuals with multiple sclerosis (MS) on their path to recovery from a relapse. If this project proves successful, it can therefore help optimize clinical practice and provide a significant contribution to the treatment of relapsing-remitting sclerosis.
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History
Started
May 2025
Main results due
Dec 2027
Finished
Dec 2027