Optimising Access to Vocational Rehabilitation Through Multiple Sclerosis Charities: A Feasibility Randomised Controlled Trial

Not yet recruitingNot a drug-phase studyMS (type not specified)NCT06966115

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Multiple Sclerosis Vocational Rehabilitation (MSVR)

What it measured

Main measures

  • Health-related quality of life

    At baseline, and -6, -9 and 12-months post-randomisation.

    Quality of life (reported by participants)
  • Work Productivity and Activity Impairment Questionnaire- Multiple Sclerosis

    At baseline, and -6, -9 and 12-months post-randomisation.

Other measures (8)

  • Goal Attaiment Scaling

    At baseline, and -6, -9 and 12-months post-randomisation.

  • Patient Health Questionnaire - 9 (PHQ-9)

    At baseline, and -6, -9 and 12-months post-randomisation.

    Mood and sleep
  • Generalised Anxiety Disorder - 7 (GAD-7)

    At baseline, and -6, -9 and 12-months post-randomisation.

    Mood and sleep
  • Perceived Difficulties Questionnaire

    At baseline, and -6, -9 and 12-months post-randomisation.

    Thinking and memory
  • Health-related quality of life

    At baseline, and -6, -9 and 12-months post-randomisation.

    Walking and mobilityPainMood and sleepQuality of life (reported by participants)
  • Fatigue levels

    At baseline, and -6, -9 and 12-months post-randomisation.

    Fatigue
  • Self-efficacy

    At baseline, and -6, -9 and 12-months post-randomisation.

  • Reasonable Adjustments

    At baseline, and -6, -9 and 12-months post-randomisation.

Who could take part

MS (type not specified) · 18 to 66

Show the full criteria

Inclusion criteria

1. Aged ≥18 2. Can give informed consent, 3. Can communicate in English, 4. Are in paid employment (including self-employed).

Exclusion criteria

1. Planning to retire within the next 12 months. 2. Currently receiving vocational rehabilitation support from the NHS or other employer services.

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

People with multiple sclerosis (MS) often leave the workforce prematurely due to MS symptoms and difficulties managing workplace relationships and performance. Vocational rehabilitation (VR) can improve job retention outcomes for people with MS, but there is a lack of evidence on the effectiveness of these interventions. A psychologist and occupational therapist-delivered VR intervention was previously developed to support people with MS to remain in paid employment. This programme was tested in a community setting and within the UK National Health Service (NHS). The preliminary findings demonstrate that the intervention is highly acceptable to people with MS and their employers and helped participants with MS to meet their vocational goals. However, the study also identified various barriers (e.g., lack of staff, service structure, etc.) to delivering this programme more widely within a healthcare setting. Because of this, patient and public involvement (PPI) representatives suggested testing the VR intervention within the services provided by MS charities. This approach could be beneficial to reach people with MS who might be in the earlier stages of the illness and looking for information or who have not considered discussing "work" with their healthcare providers. Therefore, the VR intervention MSVR ("multiple sclerosis vocational rehabilitation") was adapted to be delivered by non-specialists working for MS charities. Over recent years, the practice of training non-specialists to deliver evidence-based and complex interventions has increased to reach communities where there is a lack of resources or to help increase the reach of these interventions. This study aims to: 1. Explore the feasibility and acceptability of providing employment support through MS charities. 2. Determine the parameters for a future large-scale randomised controlled trial. 3. Explore the experiences of those receiving and delivering the MSVR intervention. Sixty people with MS in paid employment will be recruited to receive support with employment tailored to their needs over six months. Participants with MS will be asked to complete a booklet of questionnaires with variables known to affect employment status. Approximately 20 participants will be asked to participate in a feedback interview at the end of the intervention.

Papers

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History

    1. Started

      Jun 2025

    2. Main results due

      Jul 2027

    3. Finished

      Dec 2027

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