Investigation of the Effect of the MIND Diet on Disease Symptoms in Pa
Effects of the MIND Diet on Fatigue, Quality of Life, and Brain Fog in Patients With Multiple Sclerosis: A Randomized Controlled Trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- MIND Diet (Mediterranean-DASH Intervention for Neurodegenerative Delay)
- Traditional healthy nutrition program specific to Turkey
What it measured
Main measures
The Effect of the MIND Diet on Quality of Life
12 weeks from the start of the intervention
Thinking and memoryFatigueBladder, bowel and sexual functionQuality of life (reported by participants)Effect of the MIND diet on fatigue in MS patients
12 weeks from the start of the intervention
FatigueThe effect of the MIND diet on brain fog in MS patients
12 weeks from the start of the intervention
Other measures (2)
The effect of the MIND diet on blood parameters
At the end of 12 weeks after the start of the intervention
Effect of the applied MIND diet on body composition
After 12 weeks of MIND diet or healthy eating program application
Physical function
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Adult MS patients between the ages of 18-65 diagnosed according to the 2017 McDonald criteria * Having been diagnosed with MS at least three months ago; patients are called for routine check-ups in the first and third months after starting treatment, as liver function tests and/or hemogram values may be impaired due to the treatment they started when they are newly diagnosed with MS. For this reason, it was planned to include patients whose check-ups were completed and no unexpected changes were observed in the blood parameters table due to the medication. * No DMT change in the last 6 months * Patients who use their medications regularly * Not using nutritional support or supplements * Patients with an EDSS score of ≤6 * Patients with a body mass index (BMI) between 18.5-24.9 kg/m2
Exclusion criteria
* MS patients who are pregnant or lactating * Having another chronic metabolic disease and/or having had surgery in the last 3 months * MS patients with limb deficiency * MS patients on a special diet * Patients using antidepressants and/or mood stabilizers * Having had an attack and/or receiving steroid treatment in the last month
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The planned parallel group, randomized controlled study design will be used to determine the effects of the MIND diet applied to MS patients on fatigue, quality of life, technological function and brain fog and to contribute to the scientific literature. This study document will also determine the scope of the MIND diet for MS details. The regular questions it aims to answer are as follows: * Is the MIND diet applied to MS treatments effective on quality of life compared to traditional healthy nutrition? * Is the MIND diet applied to MS treatments effective on fatigue compared to traditional healthy nutrition therapy? * Is the MIND diet applied to MS treatments effective on brain fog compared to traditional healthy nutrition therapy? In this study, the MIND diet will be controlled with a traditional healthy nutrition program specific to Türkiye to evaluate the effect of the MIND diet on MS disease. Participants: * Adhere to your specially prepared diet for 3 months * Participate in online meetings with researchers every week to check compliance with the diets * Visit the hospital for a check-up at the end of 3 months The collected study data will be analyzed in a computer environment using the Statistical Package for Social Sciences (IBM, SPSS, version 29.0) software, and p\<0.05 is accepted as the significance level.
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History
Started
Jun 2025
Main results due
Nov 2025
Finished
Dec 2025