The Effect of DNS-Based Training Combined With PFMT on LUTS and Pelvic
Dynamic Neuromuscular Stabilization Combined With Pelvic Floor Muscle Training Improves Urinary and Pelvic Floor Outcomes in Women With Multiple Sclerosis
We could not find results for this trial
What it found
We found no results in the registry or in papers.
This trial finished 2 years ago. We found no results in the registry or in any paper that cites it.
What was tested
Treatment tested
- Pelvic Floor Muscle Training (PFMT)
- Pelvic Floor Muscle Training combined with Dynamic Neuromuscular Stabilization (PFMT+DNS)
What it measured
Main measures
Lower urinary tract symptoms (LUTS) severity
Baseline and 8 weeks after intervention
Bladder, bowel and sexual functionUrinary incontinence severity and impact on quality of life
baseline and 8 weeks
Bladder, bowel and sexual functionQuality of life (reported by participants)Overactive bladder symptoms
Baseline and 8 weeks
Bladder, bowel and sexual functionPelvic Floor Muscle Function - Vaginal Palpation
Baseline and 8 weeks
Pelvic floor muscle function - Electromyography (EMG)
Baseline and 8 weeks
Physical function
Other measures (2)
Perceived level of improvement - Global Perceived Effect Scale (GPE)
Baseline and 8 weeks
Treatment adherence - Visual Analog Scale (VAS)
Baseline and 8 weeks
Quality of life (reported by participants)
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Aged 18-65 years * Diagnosis of multiple sclerosis with an Expanded Disability Status Scale (EDSS) score below 6 * Pelvic floor muscle strength greater than grade 1 according to the Modified Oxford Scale (MOS) * No pelvic floor muscle training received in the previous six months
Exclusion criteria
* Multiple sclerosis relapse within the past month * Pregnant or within six months postpartum * Diagnosis of urinary tract infection * Any medical condition that could interfere with participation
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The goal of this randomized controlled trial is to investigate whether adding Dynamic Neuromuscular Stabilization (DNS)-based training to Pelvic Floor Muscle Training (PFMT) can improve lower urinary tract symptoms (LUTS) and pelvic floor functions in women with multiple sclerosis (MS), aged 28-54 years. The main questions it aims to answer are: Does DNS combined with PFMT improve lower urinary tract symptoms more effectively than PFMT alone? Does DNS combined with PFMT enhance pelvic floor muscle function more effectively than PFMT alone? Researchers will compare PFMT alone versus PFMT combined with DNS-based stabilization exercises to see if DNS provides additional benefits. Participants will: Perform an 8-week remotely monitored Pelvic Floor Muscle Training program. In the DNS+PFMT group, complete supervised Dynamic Neuromuscular Stabilization exercises three times a week. Undergo assessments including: Urinary Symptom Profile questionnaire, International Consultation on Incontinence Questionnaire-Short Form, Overactive Bladder Questionnaire (8-item version), Vaginal palpation using the PERFECT (Power, Endurance, Repetitions, Fast contractions, Every Contraction Timed) scheme, Electromyography (muscle electrical activity measurement) for pelvic floor muscles evaluation.
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History
Started
Sept 2023
Main results due
Sept 2024
Finished
Aug 2025