Exercise Balance Program for Fall Prevention in Multiple Sclerosis
Effects of an Otago-Based Exercise and Game-Inspired Balance Training Program on Balance, Mobility, and Fall-Related Outcomes in Individuals With Multiple Sclerosis: A Randomized Controlled Trial
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Combined Otago-Based and Game-Inspired Balance Training
Compared with
- Otago Exercise Program only
What it measured
Main measures
Balance Performance (FICSIT-4)
Baseline and immediately after completion of the 6-week intervention
Walking and mobility
Other measures (3)
Functional Mobility (Timed Up and Go Test)
Baseline and immediately after completion of the 6-week intervention
Walking and mobilityFear of Falling (Falls Efficacy Scale-International)
Baseline and immediately after completion of the 6-week intervention
Walking and mobilityWalking Limitations (12-item Multiple Sclerosis Walking Scale)
Baseline and immediately after completion of the 6-week intervention
Walking and mobility
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Confirmed diagnosis of multiple sclerosis according to the 2010 McDonald criteria. * Age between 18 and 65 years. * Ability to ambulate independently with or without an assistive device. * Ability to understand and follow exercise instructions. * Written informed consent prior to participation.
Exclusion criteria
* Presence of other neurological, musculoskeletal, or medical conditions that could significantly affect balance or mobility. * Acute relapse of multiple sclerosis at the time of enrollment. * Participation in another structured balance or fall-prevention program during the study period.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
Falls and balance impairments are common in individuals with multiple sclerosis (MS) and may negatively affect mobility, independence, confidence in daily activities, and quality of life, while increasing the risk of injury. This randomized controlled trial investigated the effects of a 6-week combined Otago-based and game-inspired balance-training program on static balance, functional mobility, fear of falling, and perceived walking ability in individuals with MS. Thirty participants with MS were randomly allocated to either an intervention group or an active control group. Both groups received fall-prevention counselling and performed home-based Otago-related exercises three times per week. The intervention group additionally received one supervised balance-training session per week using colored-circle and Twister-inspired task-oriented exercises. Outcomes were assessed at baseline and immediately after the intervention period using the FICSIT-4 for static balance, the Timed Up and Go test for functional mobility, the Falls Efficacy Scale-International (FES-I) for fear of falling, and the 12-item Multiple Sclerosis Walking Scale (MSWS-12) for perceived walking limitations.
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History
Started
Feb 2026
Main results due
May 2026
Finished
May 2026