The Effects of Tai Chi and Square Stepping Exercises on Joint Position Sense and Clinical Outcomes in Women With Multiple Sclerosis

CompletedNot a drug-phase studyRelapsing MSNCT07461987

What it found

No results found

We found no results in the registry or in papers.

What was tested

Treatment tested

  • Tai Chi
  • Square Stepping Exercise (SSE)

Compared with

  • Home-based Frenkel Coordination Exercises

What it measured

Main measures

  • Knee joint position sense

    Baseline (pre-intervention) and immediately post-intervention (Week 8).

Other measures (2)

  • Five-Repetition Sit-to-Stand Test (5STS)

    Baseline (pre-intervention) and immediately post-intervention (Week 8).

    Physical function
  • Fatigue Impact Scale (FIS)

    Baseline (pre-intervention) and immediately post-intervention (Week 8).

    Thinking and memoryFatigue

Who could take part

Relapsing MS · 20 to 45

Show the full criteria

Inclusion criteria

* Willing to participate and provide informed consent. * Diagnosed with multiple sclerosis (MS) according to the McDonald diagnostic criteria. * Relapsing-remitting MS (RRMS) phenotype. * EDSS score \< 3.5. * Female, 20-45 years of age. * No MS relapse within the past 1 month. * No lower-extremity spasticity according to the Modified Ashworth Scale (MAS).

Exclusion criteria

* Any neurological disease other than MS. * Experiencing an MS relapse during the study period. * History of orthopedic surgery that may affect balance. * Cognitive or psychiatric impairment that may interfere with study participation. * Cardiovascular or pulmonary history that may prevent participation. * Use of medications that may affect clinical assessment (e.g., antipsychotic use; continuous corticosteroid or immunosuppressive use within the past 1 month). * Participation in any other exercise program

As registered. Criteria can change, so ask the trial team or your neurologist.

About this trial

In the sponsor's words

Tai Chi is an exercise approach consisting of slow and controlled movements, whereas square stepping exercises are an exercise method in which specific step patterns are followed. The aim of this study is to comparatively examine the effects of Tai Chi and Square Stepping Exercises on knee joint position sense, lower extremity muscle strength, and fatigue levels in women with multiple sclerosis.

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History

    1. Started

      Feb 2026

    2. Main results due

      Jun 2026

    3. Finished

      Jun 2026

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