Evaluation of the Effects of Laughter Yoga on Pain Intensity, Stress, and Beta-endorphin Levels in Patients With Multiple Sclerosis

RecruitingNot a drug-phase studyMS (type not specified)NCT07524231

What it found

Still running

No result yet.

What was tested

Treatment tested

  • Laughter Yoga

What it measured

Main measures

  • Change in pain intensity measured by Visual Analog Scale (VAS) at [time point]

    Baseline and week 4

    Pain

Other measures (2)

  • Fatigue Level

    1 month

    Fatigue
  • Change in plasma beta-endorphin levels measured by ELISA at baseline and week 4

    Baseline and week 4

Who could take part

MS (type not specified) · 18 and over

Show the full criteria

Inclusion criteria

* • Being over 18 years old * Being able to communicate adequately * Volunteering to participate in the research

Exclusion criteria

* Unwillingness to participate in the study Having severe cognitive impairment that prevents understanding or participation in the intervention Having a psychiatric disorder that may affect participation in the study Experiencing an acute MS relapse during the study period Having another serious neurological or chronic disease that may affect the study outcomes Regular participation in another complementary therapy program similar to laughter yoga Communication problems that prevent participation in the intervention sessions

As registered. Criteria can change, so ask the trial team or your neurologist.

Contact details on the registry

About this trial

In the sponsor's words

This randomized controlled study aims to evaluate the effects of laughter yoga on pain intensity, fatigue, and beta-endorphin levels in patients with Multiple Sclerosis. Laughter yoga, a complementary therapy combining breathing exercises and laughter techniques, may help improve symptom management and psychological well-being in individuals with MS.

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History

    1. Started

      Mar 2026

    2. Main results due

      Jul 2026

    3. Finished

      Aug 2026

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