Behavioral and Electrophysiological Evidence of the Modulation of Fati
Behavioral and Electrophysiological Evidence of the Modulation of Fatigue in Multiple Sclerosis, Relapsing Remitting Form: a Pilot Study
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- TENS therapy
What it measured
Main measures
Motor performance
baseline
Other measures (1)
Readiness Potential
baseline
Nerve conduction tests
Who could take part
Relapsing MS · 18 to 40 · EDSS 2 to 5.5
Show the full criteria
Inclusion criteria
i) right-hand dominant; ii) diagnosis of MS, Relapsing-Remitting (RR-) form (Polman et al., 2011); iii) score at the EDSS (Kurtzke, 1983) from 2 to 5.5.
Exclusion criteria
i) relapse occurring over the previous six months; ii) a history of illness not less than one year; iii) first dose of disease-modifying or symptomatic treatments and any medication change in the previous three months; iv) reporting a score of equal to 2 or more at FSS (Kurtzke, 1983) cerebellar and brainstem scales; v) neuroimaging evidence of MS lesions at the spinal cord; vi) any known psychiatric or other neurological disorders, history of head injury, or stroke; vii)a score \< 24 (Lezak et al., 2004) at the Italian version (Magni et al., 1995) at the MMSE (Folstein et al., 1975).
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
To furnish behavioral and electrophysiological evidence of the possible modulation of fatigue in Multiple Sclerosis - relapsing remitting form, through a verbal placebo.
Papers
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History
Started
Jan 2025
Main results due
Apr 2026
Finished
Apr 2026