Local Vibration and Ankle Mobilization in Multiple Sclerosis
Effects of Local Vibration and Ankle Joint Mobilization on Muscle Tone, Proprioception, and Balance in Individuals With Multiple Sclerosis: A Randomized Controlled Trial
What it found
No result yet.
What was tested
Treatment tested
- Local Vibration
Compared with
- Ankle Joint Mobilization
What it measured
Main measures
Ankle Joint Position Sense Error
Baseline and immediately after the 6-week intervention
Other measures (2)
Muscle Mechanical Properties
Baseline and immediately after the 6-week intervention
Trunk Sway
Baseline and immediately after the 6-week intervention
Walking and mobility
Who could take part
MS (type not specified) · 18 to 65
Show the full criteria
Inclusion criteria
* Age between 18 and 65 years. * Diagnosis of multiple sclerosis confirmed by a neurologist. * Expanded Disability Status Scale (EDSS) score ≤6.0. * Ability to walk at least 100 meters, with or without an assistive device. * No MS relapse within the previous 3 months. * Willingness to participate in the study and provision of written informed consent.
Exclusion criteria
* MS relapse within the previous 3 months. * Severe cognitive impairment or cognitive problems that may interfere with communication or participation. * History of orthopedic surgery involving the lower extremity or presence of a severe orthopedic condition affecting lower-extremity function. * Vestibular system disorder or another neurological condition that may affect balance. * Any medical condition contraindicating local vibration or manual therapy. * Inability to participate regularly throughout the study period.
As registered. Criteria can change, so ask the trial team or your neurologist.
Contact details on the registryAbout this trial
In the sponsor's words
This study will investigate the effects of local vibration and ankle joint mobilization on muscle tone, proprioception, and balance in individuals with multiple sclerosis (MS). Participants will be randomly assigned to one of two treatment groups. One group will receive local vibration applied to the gastrocnemius muscle, while the other group will receive ankle joint mobilization. Both interventions will be performed three times per week for six weeks. Muscle tone, ankle joint position sense, and balance will be assessed before and after the intervention. The study aims to determine whether these interventions can improve neuromuscular and balance-related functions in individuals with MS.
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History
Started
Dec 2026
Main results due
May 2027
Finished
Jun 2027