Ai-Chi in Individuals With Multiple Sclerosis
Investigation of the Effect of Ai Chi Exercises in Individuals With Multiple Sclerosis
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Ai-Chi exercise
Compared with
- Land-Based Exercise
What it measured
Main measures
Lower Extremity Strength Assessment
Baseline and immediately after the 5-week intervention
Physical functionUpper Extremity Strength Assessment
Baseline and immediately after the 5-week intervention
Arm and hand functionPhysical functionBalance Assessment
Baseline and immediately after the 5-week intervention
Walking and mobilityFatigue Assessment
Baseline and immediately after the 5-week intervention
Thinking and memoryFatigue
Other measures (3)
Quality of Life Assessment
Baseline and immediately after the 5-week intervention
Thinking and memoryPainQuality of life (reported by participants)Mobility Assessment
Baseline and immediately after the 5-week intervention
Walking and mobilityCognitive Function Assessment
Baseline and immediately after the 5-week intervention
Thinking and memory
Who could take part
MS (type not specified) · 18 to 65 · EDSS 0 to 6.5
Show the full criteria
Inclusion criteria
* Being between 18 and 65 years of age. * Voluntarily agreeing to participate in the study. * Having a diagnosis of Multiple Sclerosis according to the McDonald criteria. * Being able to read and write. * Having an Expanded Disability Status Scale (EDSS) score between 0 and 6.5.
Exclusion criteria
* Having experienced an MS relapse within the previous 6 months. * Having a severe psychological disorder that may interfere with participation in cognitive assessments. * Having a substance dependence, including dependence on tobacco or alcohol. * Having a fear of water (aquaphobia). * Having a dermatological condition that may prevent participation in aquatic exercise therapy. * Having a history of trauma within the previous 3 months. * Being pregnant.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
The subject of this study is to examine the effects of Ai Chi-an aquatic exercise method-on balance, mobility, muscle strength, quality of life, depression, fatigue, and cognitive functions in individuals diagnosed with Multiple Sclerosis (MS), in comparison with land-based exercises. Developed to address the physical and cognitive symptoms associated with MS, this study aims to evaluate the effectiveness of Ai Chi exercises-performed in water-as an alternative and/or complementary rehabilitation method alongside traditional land-based exercises. In this context, the research seeks to offer an innovative approach to enhancing the quality of life and functional capacity of individuals with MS.
Papers
Background
Becker BE. Aquatic therapy: scientific foundations and clinical rehabilitation applications. PM R. 2009 Sep;1(9):859-72. doi: 10.1016/j.pmrj.2009.05.017.Background
Bayraktar D, Guclu-Gunduz A, Yazici G, Lambeck J, Batur-Caglayan HZ, Irkec C, Nazliel B. Effects of Ai-Chi on balance, functional mobility, strength and fatigue in patients with multiple sclerosis: a pilot study. NeuroRehabilitation. 2013;33(3):431-7. doi: 10.3233/NRE-130974.Background
Nazary Soltan Ahmad S, Shojaedin SS, Tazji MK. Comparative effects of dual-task training versus combined exercise training in water and on land on patients with multiple sclerosis: a study protocol of a randomised factorial trial. BMJ Open. 2025 Jan 15;15(1):e086941. doi: 10.1136/bmjopen-2024-086941.
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History
Started
Jan 2026
Main results due
Jan 2026
Finished
Mar 2026