Observational Study of Early Interferon beta 1-a Treatment in High Ris
Observational Study of Early Interferon beta 1-a Treatment in High Risk Subjects after CIS (SET Study)
What it found
We found no results in the registry or in papers.
What was tested
Treatment tested
- Interferon beta-1a
Interferon alpha/beta receptor agonist
What it measured
Main measures
Clinical endpoints include:
Who could take part
Early (CIS/RIS)
Show the full criteria
Inclusion criteria
Inclusion: · Clinically isolated syndrome suspected from demyelinating event (no better explanation for present symptoms) Exclusion: · The clinical diagnosis of Multiple Sclerosis is definite (the second attack occurs before the baseline visit)
Exclusion criteria
Not separately supplied in the registry.
As registered. Criteria can change, so ask the trial team or your neurologist.
About this trial
In the sponsor's words
To determine which high-risk patient groups presenting with a clinically isolated syndrome (CIS) suggestive of multiple sclerosis may have the best clinical outcome from treatment with interferon beta 1-a (Avonex). This study will evaluate the conversion pattern to clinically definite multiple sclerosis in high risk CIS patients treated with (IFN beta-1a IM) (Avonex) during a follow up period of 4 years and will determine risk factors for conversion to CDMS under treatment. Each clinical and MRI end point will be evaluated with its relation to the baseline clinical and MRI characteristics.
Papers
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History
Started
Jul 2005